We introduce the Piquasso quantum programming framework, a full-stack open-source software platform for the simulation and programming of photonic quantum computers. Piquasso can be programmed via a high-level Python programming interface enabling users to perform efficient quantum computing with di…
Since the advent of CRISPR-Cas9, a groundbreaking gene-editing technology that enables precise genomic modifications via a short RNA guide sequence, there has been a marked increase in the accessibility and application of this technology across various fields. The success of CRISPR-Cas9 has spurred …
CRISPR/Cas has the potential to revolutionize medicine, agriculture, and biology. Understanding the trajectory of CRISPR research, how it is influenced and who pays for it, is an essential research policy question. We use a combination of methods to map, via quantitative content analysis of CRISPR p…
CRISPR genome engineering and single-cell RNA sequencing have accelerated biological discovery. Single-cell CRISPR screens unite these two technologies, linking genetic perturbations in individual cells to changes in gene expression and illuminating regulatory networks underlying diseases. Despite t…
CRISPR-based genome editing has revolutionized biotechnology, yet optimizing guide RNA (gRNA) design for efficiency and safety remains a critical challenge. Recent advances (2020--2025, updated to reflect current year if needed) demonstrate that artificial intelligence (AI), especially deep learning…
An outbreak of betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 began in Wuhan, China in December 2019. COVID-19, the disease associated with SARS-CoV-2 infection, rapidly spread to produce a global pandemic. We report development of a rapid (<40 min), easy-to-implement and accurate …
Genome editing has been a transformative force in the life sciences and human medicine, offering unprecedented opportunities to dissect complex biological processes and treat the underlying causes of many genetic diseases. CRISPR-based technologies, with their remarkable efficiency and easy programm…
Artificial intelligence is observed to age not through chronological time but through structural asymmetries in memory performance. In large language models, semantic cues such as the name of the day often remain stable across sessions, while episodic details like the sequential progression of exper…
This paper leverages various philosophical and ontological frameworks to explore the concept of embodied artificial general intelligence (AGI), its relationship to human consciousness, and the key role of the metaverse in facilitating this relationship. Several theoretical frameworks underpin this e…
The NLLG (Natural Language Learning & Generation) arXiv reports assist in navigating the rapidly evolving landscape of NLP and AI research across cs.CL, cs.CV, cs.AI, and cs.LG categories. This fourth installment captures a transformative period in AI history - from January 1, 2023, following ChatGP…