Scholar iON
Academic Synthesis
The collected body of research showcases diverse applications of mathematical and probabilistic theories across decision-making, finance, and biomedical fields. Liu and Wang (2019) advance fuzzy set theory by proposing a new multiple-attribute decision-making method using q-rung orthopair fuzzy numbers, enhancing decision-making processes through superior information expression and operational rules. Crépey and Song (2017) and Kramkov and Predoiu (2011) delve into the intricacies of probability measures and martingales, addressing critical issues in financial mathematics such as invariance times and endogenous completeness, respectively. Meanwhile, Pontrelli et al. (2019) apply mathematical modeling to pH-responsive drug delivery systems, demonstrating the potential of quantitative models to predict and optimize drug release profiles. This corpus highlights the interdisciplinary reach of mathematical modeling and probability theory, underscoring their significance in advancing both theoretical understanding and practical applications across various domains.
The theory of <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-rung orthopair fuzzy sets (<inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-ROFSs) proposed by Yager effectively describes fuzzy information in the real world. Because <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-ROFSs contain the parameter <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula> and can adjust the range of expressed fuzzy information, they are superior to both intuitionistic and Pythagorean fuzzy sets. Archimedean T-norm and T-conorm (ATT) is an important tool used to generate operational rules based on the <italic>q</italic>-rung orthopair fuzzy numbers (<inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-ROFNs). In comparison, the Bonferroni mean (BM) operator has an advantage because it considers the interrelationships between the different attributes. Therefore, it is an important and meaningful innovation to extend the BM operator to the <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-ROFNs based upon the ATT. In this paper, we first discuss <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-rung orthopair fuzzy operational rules by using ATT. Furthermore, we extend BM operator to the <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-ROFNs and propose the <inline-formula><tex-math notation="LaTeX">$q$</tex-math></inline-formula>-rung orthopair fuzzy Archimedean BM <inline-formula><tex-math notation="LaTeX">$(q\hbox{-}{ROFABM})$</tex-math></inline-formula> operator and the <italic>q</italic>-rung orthopair fuzzy weighted Archimedean BM <inline-formula><tex-math notation="LaTeX">$(q\hbox{-}{ROFWABM})$</tex-math></inline-formula> operator and study their desirable properties. Then, a new multiple-attribute decision-making (MADM) method is developed based on <inline-formula><tex-math notation="LaTeX">$q\hbox{-}{ROFWABM}$</tex-math></inline-formula> operator. Finally, we use a practical example to verify effectiveness and superiority by comparing to other existing methods.
On a probability space $(Ω,\mathcal{A},\mathbb{Q})$ we consider two filtrations $\mathbb{F}\subset \mathbb{G}$ and a $\mathbb{G}$ stopping time $θ$ such that the $\mathbb{G}$ predictable processes coincide with $\mathbb{F}$ predictable processes on $(0,θ]$. In this setup it is well-known that, for any $\mathbb{F}$ semimartingale $X$, the process $X^{θ-}$ ($X$ stopped "right before $θ$") is a $\mathbb{G}$ semimartingale.Given a positive constant $T$, we call $θ$ an invariance time if there exists a probability measure $\mathbb{P}$ equivalent to $\mathbb{Q}$ on $\mathcal{F}\_T$ such that, for any $(\mathbb{F},\mathbb{P})$ local martingale $X$, $X^{θ-}$ is a $(\mathbb{G},\mathbb{Q})$ local martingale. We characterize invariance times in terms of the $(\mathbb{F},\mathbb{Q})$ Azéma supermartingale of $θ$ and we derive a mild and tractable invariance time sufficiency condition. We discuss invariance times in mathematical finance and BSDE applications.
Let $\mathbb{Q}$ and $\mathbb{P}$ be equivalent probability measures and let $ψ$ be a $J$-dimensional vector of random variables such that $\frac{d\mathbb{Q}}{d\mathbb{P}}$ and $ψ$ are defined in terms of a weak solution $X$ to a $d$-dimensional stochastic differential equation. Motivated by the problem of \emph{endogenous completeness} in financial economics we present conditions which guarantee that every local martingale under $\mathbb{Q}$ is a stochastic integral with respect to the $J$-dimensional martingale $S_t \set \mathbb{E}^{\mathbb{Q}}[ψ|\mathcal{F}_t]$. While the drift $b=b(t,x)$ and the volatility $σ= σ(t,x)$ coefficients for $X$ need to have only minimal regularity properties with respect to $x$, they are assumed to be analytic functions with respect to $t$. We provide a counter-example showing that this $t$-analyticity assumption for $σ$ cannot be removed.
Drug delivery systems represent a promising strategy to treat cancer and to overcome the side effects of chemotherapy. In particular, polymeric nanocontainers have attracted major interest because of their structural and morphological advantages and the variety of polymers that can be used, allowing the synthesis of materials capable of responding to the biochemical alterations of the tumour microenvironment. While experimental methodologies can provide much insight, the generation of experimental data across a wide parameter space is usually prohibitively time consuming and/or expensive. To better understand the influence of varying design parameters on the drug release profile and drug kinetics involved, appropriately-designed mathematical models are of great benefit. Here, we developed a novel mathematical model to describe drug transport within, and release from, a hollow nanocontainer consisting of a core and a pH-responsive polymeric shell. The two-layer mathematical model fully accounts for drug dissolution, diffusion and interaction with polymer. We generated experimental drug release profiles using daunorubicin and [Cu(TPMA)(Phenantroline)](ClO_4)_2 as model drugs, for which the nanocontainers exhibited excellent encapsulation ability. The in vitro drug release behaviour was studied under different conditions, where the system proved capable of responding to the selected pH stimuli by releasing a larger amount of drug in an acidic than in the physiological environments. By comparing the results of the mathematical model with our experimental data, we were able to identify the model parameter values that best-fit the data and demonstrate that the model is capable of describing the phenomena at hand. The proposed methodology can be used to describe and predict the release profiles for a variety of drug delivery systems.
In this lecture I discuss some aspects of MKM, Mathematical Knowledge Management, with particuar emphasis on information storage and information retrieval.
This work aims at showing the relevance and the applications possibilities of the Fibonacci sequence, and also its q-deformed or quantum extension, in the study of the genetic code(s). First, after the presentation of a new formula, an indexed double Fibonacci sequence, comprising the first six Fibonacci numbers, is shown to describe the 20 amino acids multiplets and their degeneracy as well as a characteristic pattern for the 61 meaningful codons. Next, the twenty amino acids, classified according to their increasing atom-number (carbon, nitrogen, oxygen and sulfur), exhibit several Fibonacci sequence patterns. Several mathematical relations are given, describing various atom-number patterns. Finally, a q-Fibonacci simple phenomenological model, with q a real deformation parameter, is used to describe, in a unified way, not only the standard genetic code, when q=1, but also all known slight variations of this latter, when q~1, as well as the case of the 21st amino acid (Selenocysteine) and the 22nd one (Pyrrolysine), also when q~1. As a by-product of this elementary model, we also show that, in the limit q=0, the number of amino acids reaches the value 6, in good agreement with old and still persistent claims stating that life, in its early development, could have used only a small number of amino acids.
A new concept called biased derivative is proposed. It has a potential to better understand and model some aspects of dynamical systems associated with creating bubbles.
Politics is everywhere. In this paper, I propose a simple model to demonstrate political behavior in human society.
The International Congress of Mathematicians (ICM), inaugurated in 1897, is the greatest effort of the mathematical community to strengthen international communication and connections across all mathematical fields. Meetings of the ICM have historically hosted some of the most prominent mathematicians of their time. Receiving an invitation to present a talk at an ICM signals the high international reputation of the recipient, and is akin to entering a `hall of fame for mathematics'. Women mathematicians attended the ICMs from the start. With the invitation of Laura Pisati to present a lecture in 1908 in Rome and the plenary talk of Emmy Noether in 1932 in Zurich, they entered the grand international stage of their field. At the congress in 2014 in Seoul, Maryam Mirzakhani became the first woman to be awarded the Fields Medal, the most prestigious award in mathematics. In this article, we dive into assorted data sources to follow the footprints of women among the ICM invited speakers, analyzing their demographics and topic distributions, and providing glimpses into their diverse biographies.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), linked with CRISPR associated (CAS) genes, play a profound role in the interactions between phage and their bacterial hosts. It is now well understood that CRISPR-CAS systems can confer adaptive immunity against bacteriophage infections. However, the possibility of failure of CRISPR immunity may lead to a productive infection by the phage (cell lysis) or lysogeny. Recently, CRISPR-CAS genes have been implicated in changes to group behaviour, including biofilm formation, of the bacterium Pseudomonas aeruginosa when lysogenized. For lysogens with a CRISPR system, another recent experimental study suggests that bacteriophage re-infection of previously lysogenized bacteria may lead to cell death. Thus CRISPR immunity can have complex effects on phage-host-lysogen interactions, particularly in a biofilm. In this contribution, we develop and analyse a series of models to elucidate and disentangle these interactions. From a therapeutic standpoint, CRISPR immunity increases biofilm resistance to phage therapy. Our models predict that lysogens may be able to displace CRISPR-immune bacteria in a biofilm, and thus suggest strategies to eliminate phage resistant biofilms.